Individual
Attribute: Individual Gender¶
| Valid Value | Description | Ontology |
|---|---|---|
| Female | An individual who belongs to the sex that normally produces ova. | NCIT:C16576 |
| Male | An individual who belongs to the sex that normally produces sperm. | NCIT:C20197 |
| Intersex | Refers to an individual who was born with genitalia, chromosomes, or reproductive organs that do not fit typical definitions for either male or female. | NCIT:C45908 |
| Unknown | Not known, observed, recorded, or reported as unknown by the data contributor. | NCIT:C17998 |
| Unspecified | Not stated explicitly or in detail. | NCIT:C38046 |
| Not Reported | Not provided or available. | NCIT:C43234 |
Attribute: Individual Primary Tumor Stage¶
| Valid Value | Description | Ontology |
|---|---|---|
| Not Reported | Not provided or available. | NCIT:C43234 |
| T0 | No evidence of primary tumor | NCIT:C48719 |
| T1 | A clinical and/or pathologic primary tumor TNM finding indicating that the cancer is limited to the site of growth. | NCIT:C48720 |
| T1a | A general term that refers to a TNM finding of a primary tumor limited to the site of growth; the specific definition of T1a depends on the type of cancer. | NCIT:C48721 |
| T1a1 | A general term that refers to a TNM finding of a primary tumor limited to the site of growth; the specific definition of T1a1 depends on the type of cancer. | NCIT:C188292 |
| T1a2 | A general term that refers to a TNM finding of a primary tumor limited to the site of growth; the specific definition of T1a2 depends on the type of cancer. | NCIT:C188293 |
| T1b | A general term that refers to a TNM finding of a primary tumor limited to the site of growth; the specific definition of T1b depends on the type of cancer. | NCIT:C48722 |
| T1b1 | A general term that refers to a TNM finding of a primary tumor limited to the site of growth; the specific definition of T1b1 depends on the type of cancer. | NCIT:C188294 |
| T1b2 | A general term that refers to a TNM finding of a primary tumor limited to the site of growth; the specific definition of T1b2 depends on the type of cancer. | NCIT:C188295 |
| T1c | A general term that refers to a TNM finding of a primary tumor limited to the site of growth; the specific definition of T1c depends on the type of cancer. | NCIT:C48723 |
| T1mi | A term that refers to a TNM finding of a primary tumor limited to the site of growth and indicates microinvasion only. | NCIT:C95805 |
| T2 | A general term that refers to a TNM finding of primary tumor growth beyond the level of in situ cancer, minimal subepithelial invasion, or minimal greatest diameter; the specific definition depends on the type of cancer. | NCIT:C48724 |
| T2a | A general term that refers to a TNM finding of primary tumor growth beyond the level of in situ cancer; the specific definition of T2a depends on the type of cancer. | NCIT:C48725 |
| T2a1 | A general term that refers to a TNM finding of a primary tumor; the specific definition of T2a1 depends on the type of cancer. | NCIT:C188296 |
| T2a2 | A general term that refers to a TNM finding of a primary tumor; the specific definition of T2a2 depends on the type of cancer. | NCIT:C188297 |
| T2b | A general term that refers to a TNM finding of primary tumor growth beyond the level of in situ cancer; the specific definition of T2b depends on the type of cancer. | NCIT:C48726 |
| T2c | A general term that refers to a TNM finding of primary tumor growth beyond the level of in situ cancer; the specific definition of T2c depends on the type of cancer. | NCIT:C48727 |
| T2d | A TNM stage finding term for ophthalmic sites melanoma staging, indicating tumor size category 2 with specific extension or caruncular criteria. | NCIT:C148411 |
| T3 | A clinical and/or pathologic primary tumor TNM finding usually indicating that the cancer is locally invasive, without infiltration of adjacent structures. | NCIT:C48728 |
| T3a | A general term that refers to a TNM finding of a primary tumor usually indicating that the cancer is locally invasive; the specific definition of T3a depends on the type of cancer. | NCIT:C48729 |
| T3b | A general term that refers to a TNM finding of a primary tumor usually indicating that the cancer is locally invasive; the specific definition of T3b depends on the type of cancer. | NCIT:C48730 |
| T3c | A general term that refers to a TNM finding of a primary tumor usually indicating that the cancer is locally invasive; the specific definition of T3c depends on the type of cancer. | NCIT:C48731 |
| T3d | A TNM finding term for melanoma or retinoblastoma staging, indicating tumor size category 3 with ciliary body involvement, specific conjunctival extension, or scleral invasion criteria. | NCIT:C148412 |
| T4 | A clinical and/or pathologic primary tumor TNM finding indicating direct invasion of adjacent structures by cancer. | NCIT:C48732 |
| T4a | A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures; the specific definition of T4a depends on the type of cancer. | NCIT:C48733 |
| T4b | A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures; the specific definition of T4b depends on the type of cancer. | NCIT:C48734 |
| T4c | A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures; the specific definition of T4c depends on the type of cancer. | NCIT:C48735 |
| T4d | A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures; the specific definition of T4d depends on the type of cancer. | NCIT:C48736 |
| T4e | A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures; the specific definition of T4e depends on the type of cancer. | NCIT:C188298 |
| T5 | An antiquated primary tumor finding term that refers to colorectal cancer which has spread by direct extension beyond the immediately adjacent organs or tissues (AJCC 1st Ed.). | NCIT:C132010 |
| Ta | A term that refers to a TNM finding of a primary, non-invasive papillary carcinoma. | NCIT:C96025 |
| Tis | Carcinoma in situ (early cancer that has not spread to neighboring tissue) | NCIT:C48738 |
| Tis (DCIS) | Breast cancer with a finding of ductal carcinoma in situ. | NCIT:C139414 |
| Tis (LCIS) | Breast cancer with a finding of lobular carcinoma in situ (per AJCC 6th and 7th editions; LCIS was removed from TNM staging in the 8th edition). | NCIT:C48976 |
| Tis (Paget's) | Paget disease of the nipple not associated with invasive carcinoma and/or carcinoma in situ in the underlying breast parenchyma. | NCIT:C139415 |
| TX | Primary tumor cannot be evaluated | NCIT:C48737 |
| Unknown | Not known, observed, recorded, or reported as unknown by the data contributor. | NCIT:C17998 |
Attribute: Individual Tumor Lymph Node Stage¶
| Valid Value | Description | Ontology |
|---|---|---|
| N0 | No regional lymph node involvement (no cancer found in the lymph nodes) | NCIT:C48705 |
| N0 (i+) | A regional lymph node TNM finding indicating that there are malignant cells in regional lymph node(s) no greater than 0.2 mm and are detected by hematoxylin and eosin stain or immunohistochemistry. | NCIT:C95922 |
| N0 (i-) | A regional lymph node TNM finding indicating that there is no evidence of regional lymph node metastasis histologically, and immunohistochemistry is negative. | NCIT:C95921 |
| N0 (mol+) | A regional lymph node TNM finding indicating that there is no evidence of regional lymph node metastasis histologically and by immunohistochemistry, but the molecular analysis (RT-PCR) is positive. | NCIT:C95925 |
| N0 (mol-) | A regional lymph node TNM finding indicating that there is no evidence of regional lymph node metastasis histologically and molecular analysis (RT-PCR) is negative. | NCIT:C95923 |
| N1 | A general term that refers to a TNM finding of cancer metastases usually in a limited number of regional lymph nodes. | NCIT:C48706 |
| N1a | A general term that refers to a TNM finding of cancer metastases usually in a limited number of regional lymph nodes, subclassified as N1a. | NCIT:C48707 |
| N1b | A general term that refers to a TNM finding of cancer metastases usually in a limited number of regional lymph nodes, subclassified as N1b. | NCIT:C48708 |
| N1bI | A regional lymph node TNM finding indicating that there is metastasis to 1-3 nodes. The metastasis is greater than 2 mm and all are less than 20 mm. | NCIT:C95929 |
| N1bII | A regional lymph node TNM finding indicating that there is metastasis to four or more nodes. The metastasis is greater than 2 mm and all are less than 20 mm. | NCIT:C95935 |
| N1bIII | A regional lymph node TNM finding indicating that the tumor extends beyond the lymph node capsule and is less than 20 mm. | NCIT:C95936 |
| N1bIV | A regional lymph node TNM finding indicating that the metastases to the lymph nodes are more than 20 mm. | NCIT:C95937 |
| N1c | A general term that refers to a TNM finding of cancer metastases usually in a limited number of regional lymph nodes, subclassified as N1c. | NCIT:C48709 |
| N1mi | A regional lymph node TNM finding indicating the presence of micrometastases (greater than 0.2 mm and/or more than 200 cells, but none greater than 2.0 mm). | NCIT:C95955 |
| N2 | A general term that refers to a TNM finding of cancer metastases in several regional lymph nodes. | NCIT:C48786 |
| N2a | A general term that refers to a TNM finding of cancer metastases in several regional lymph nodes, subclassified as N2a. | NCIT:C48711 |
| N2b | A general term that refers to a TNM finding of cancer metastases in several regional lymph nodes, subclassified as N2b. | NCIT:C48712 |
| N2c | A general term that refers to a TNM finding of cancer metastases in several regional lymph nodes, subclassified as N2c. | NCIT:C48713 |
| N3 | A general term that refers to a TNM finding of cancer metastases in multiple lymph nodes. | NCIT:C48714 |
| N3a | A general term that refers to a TNM finding of cancer metastases in multiple lymph nodes, subclassified as N3a. | NCIT:C48715 |
| N3b | A general term that refers to a TNM finding of cancer metastases in multiple lymph nodes, subclassified as N3b. | NCIT:C48716 |
| N3c | A general term that refers to a TNM finding of cancer metastases in multiple lymph nodes, subclassified as N3c. | NCIT:C48717 |
| N4 | A general term that refers to a TNM finding of cancer metastases in multiple lymph nodes, subclassified as N4. | NCIT:C96026 |
| NX | Regional lymph nodes cannot be evaluated | NCIT:C48718 |
| Unknown | Not known, observed, recorded; or reported as unknown by the data contributor. | NCIT:C17998 |
| Not Reported | Not provided or available. | NCIT:C43234 |
Attribute: Individual Metastasis Stage¶
| Valid Value | Description | Ontology |
|---|---|---|
| M0 | No distant metastasis (cancer has not spread to other parts of the body) | NCIT:C48699 |
| M1 | A clinical and/or pathologic distant metastasis TNM finding indicating the spread of cancer to distant anatomic sites. | NCIT:C48700 |
| M1a | A distant metastasis TNM finding indicating the spread of cancer to a single distant organ or site; the specific meaning varies by cancer type. | NCIT:C48701 |
| M1b | A distant metastasis TNM finding indicating the spread of cancer to multiple distant organs or sites; the specific meaning varies by cancer type. | NCIT:C48702 |
| M1c | A distant metastasis TNM finding indicating the spread of cancer to additional distant anatomic sites; the specific meaning varies by cancer type. | NCIT:C48703 |
| MX | A distant metastasis TNM finding indicating that the status of distant metastasis cannot be assessed. | NCIT:C48704 |
| cM0 (i+) | A distant metastasis TNM finding indicating that there is no evidence of distant metastasis clinically or by radiologic studies, but there are small numbers of cells detected by special studies in the blood and bone marrow, or there is tiny metastasis (no larger than 0.2 mm) detected in nonregional lymph nodes. | NCIT:C95956 |
| Unknown | Not known, observed, recorded, or reported as unknown by the data contributor. | NCIT:C17998 |
| Not Reported | An indication that the required information was not provided. | NCIT:C43234 |
Attribute: Individual Recurrence Status¶
| Valid Value | Description | Ontology |
|---|---|---|
| Yes | The affirmative response to a question. | NCIT:C49488 |
| Unknown | Not known, observed, recorded, or reported as unknown by the data contributor. | NCIT:C17998 |
| Not Reported | Not provided or available. | NCIT:C43234 |
| Not Applicable | Determination of a value is not relevant in the current context. | NCIT:C48660 |
| Not Allowed to Collect | An indicator that specifies that a collection event was not permitted. | NCIT:C141478 |
| No | The non-affirmative response to a question. | NCIT:C49487 |
| Censored | When information on time-to-event is not available due to loss to follow-up or non-occurrence of outcome event before the trial end. | NCIT:C118962 |
Attribute: Individual Vital Status¶
| Valid Value | Description | Ontology |
|---|---|---|
| Unspecified | Not stated explicitly or in detail. | NCIT:C38046 |
| Unknown | Not known, observed, recorded, or reported as unknown by the data contributor. | NCIT:C17998 |
| Dead | The cessation of life. | NCIT:C28554 |
| Alive | Showing characteristics of life; displaying signs of life. | NCIT:C37987 |
| Not reported | Not provided or available. | NCIT:C43234 |